Yes, absolutely — CleanMyPC is still safe, stable, fully functional, and supported.
The most important changes are these:
- Windows 11 is the last supported OS for CleanMyPC.
- There will be no new features in CleanMyPC, only critical bug fixes.
- CleanMyPC is moving from subscriptions to licenses; all active subscribers will receive a lifetime license, free of charge.
For more details, see this article.